Side effects
Nervecept Side Effects: What Each Ingredient Can Do, and Is Nervecept Safe?
No study has tracked Nervecept side effects, so the known risks come from its eight ingredients. The serious ones are a shellfish allergy, since it contains crayfish, and extra bleeding risk with blood thinners. Mild stomach upset is the most common report. Most doses are small, but ask your doctor first if you take daily medicine.
Written by the Nervecept label deskUpdated
The short answer01
What are the side effects of Nervecept?
The likely side effects of Nervecept are mild, such as an upset stomach or loose stools. The serious risks are an allergic reaction in people allergic to shellfish and bleeding problems in people on blood thinners.
No trial has given Nervecept to a group and counted problems. What we know comes from each ingredient. Those sources mostly used doses far larger than one capsule.
That cuts both ways. Small doses make many side effects less likely. An allergy is different. A trace of shellfish protein can trigger a reaction in someone sensitive.
Ingredient by ingredient02
What side effects can each Nervecept ingredient cause?
Each of the eight ingredients has its own safety record. Glucosamine and turmeric carry the most cautions; methionine and MSM, at 8 mg each, carry almost none.
The amount column shows how much one capsule holds. Side effects in the sources were usually seen at the studied amount, not at the capsule amount.
| Ingredient | Per capsule | Reported side effects and cautions |
|---|---|---|
| Glucosamine sulfate | 500 mg | About as safe as placebo in trials (Cochrane, Glucosamine for OA (2005)); allergy risk with shellfish; may affect blood glucose; may raise INR with warfarin (NCCIH, Glucosamine and Chondroitin) (MSKCC, Glucosamine) |
| Boswellia serrata | 67 mg | Allergic skin reactions reported; may add to bleeding risk with blood thinners (MSKCC, Boswellia) |
| Chondroitin sulfate | 50 mg | Serious events less common than placebo in short trials (Cochrane, Chondroitin for OA (2015)); may add to warfarin's effect (NCCIH, Glucosamine and Chondroitin) |
| Turmeric | 50 mg | Rare liver injury reports; may raise bleeding risk; kidney stone caution; may be unsafe in pregnancy (NCCIH, Turmeric) (MSKCC, Turmeric) |
| Quercetin | 8 mg | May affect some drug-processing enzymes; one case of raised INR on warfarin (MSKCC, Quercetin) |
| Methionine | 8 mg | An essential amino acid from protein food; 8 mg is a food-like amount (MedlinePlus, Amino acids) |
| MSM | 8 mg | Few, mild side effects at up to 4 g a day (Butawan et al., MSM review 2017) |
| Bromelain | 8 mg | Stomach upset and diarrhea most common (NCCIH, Bromelain); allergic reactions; bleeding risk with blood thinners (MSKCC, Bromelain) |
Read the full profile of any line from the ingredients page.
Safety03
Is Nervecept safe to take every day?
Nervecept is likely low risk for most healthy adults at one capsule a day. Still, no one has tested its safety directly. The label caution names the people who should ask a physician before the first dose.
The caution reads: "Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement." It adds: "Keep out of reach of children. Do not use if safety seal is damaged or missing."
FDA does not review supplements for safety before they are sold, so the company is responsible for what is in the bottle (FDA 101: Dietary Supplements). Labels on supplements may not always match the contents (NCCIH, Using Supplements Wisely), and no lab report for Nervecept is published.
Interactions04
Which medicines can interact with Nervecept?
Blood thinners are the main medicines that may interact with Nervecept. Several ingredients have reports of raising bleeding risk or INR. Bromelain may also raise some antibiotic levels.
Show the bottle to your pharmacist, who can check all eight lines against your list. Tell every provider, including your dentist, what supplements you take (NCCIH, Using Supplements Wisely).
| Medicine type | Examples | Ingredients involved | Possible effect |
|---|---|---|---|
| Anticoagulants | Warfarin, apixaban, rivaroxaban | Glucosamine, chondroitin, turmeric, quercetin, bromelain, boswellia | Higher INR or more bruising and bleeding (MSKCC, Glucosamine) (MSKCC, Turmeric) (MSKCC, Quercetin) (MSKCC, Bromelain) |
| Antiplatelets | Clopidogrel, daily aspirin | Turmeric, bromelain, boswellia | More bleeding risk (MSKCC, Boswellia) (MSKCC, Turmeric) |
| Diabetes medicines | Metformin, insulin | Glucosamine | Blood glucose may shift (NCCIH, Glucosamine and Chondroitin) (MSKCC, Glucosamine) |
| Tetracycline antibiotics | Doxycycline, tetracycline | Bromelain | Higher antibiotic blood levels (MSKCC, Bromelain) |
| Drugs cleared by CYP3A4 or CYP2C19 | Many; ask a pharmacist | Quercetin | Drug levels may change (MSKCC, Quercetin) |
| Surgery and anesthesia | Any planned procedure | Several | Bleeding risk; tell your surgeon (NCCIH, Using Supplements Wisely) |
Never stop or change a prescribed dose to make room for Nervecept. If there is a clash, the supplement is what goes. More in our guide to supplements and nerve medicines.
Allergy05
Can Nervecept cause an allergic reaction?
Yes, Nervecept can cause an allergic reaction, most likely in people allergic to shellfish. The label says "CONTAINS: Shellfish (Crayfish)." because the glucosamine is made from crustacean shells.
Two smaller allergy risks sit in the formula too. Bromelain comes from pineapple stem and has allergy reports (MSKCC, Bromelain), and boswellia has caused allergic skin reactions (MSKCC, Boswellia).
Hives, itching or swelling after a capsule means stop and call your doctor. Trouble breathing or a swelling throat means call 911. The full steps are on the shellfish allergen page.
Nervecept: from $49 a bottle30 capsules · 2, 3 or 6 bottles · free US shipping on 3 or 6 · 60-day guarantee
See packsLiver, sugar, kidneys06
Can Nervecept affect the liver, blood sugar or kidneys?
Nervecept has no reports of its own, but two ingredients carry organ cautions. Turmeric has rare liver injury reports, and glucosamine may raise blood glucose in some people.
NCCIH says to stop a turmeric product and call a provider if you notice fatigue, nausea, dark urine or yellow skin or eyes (NCCIH, Turmeric). Most cases involved strong, highly absorbed curcumin products. Nervecept lists 50 mg of plain turmeric root.
If you have diabetes, check your glucose as usual and tell your doctor about the capsule (NCCIH, Glucosamine and Chondroitin). People prone to kidney stones should ask before taking turmeric (MSKCC, Turmeric).
When to stop07
When should you stop Nervecept and call a doctor?
Stop Nervecept and call a doctor for hives, swelling, ongoing stomach pain, odd bruising or signs of liver trouble. Some nerve symptoms need care right away, whatever you are taking.
After a bad reaction, FDA asks you to stop the product, get care and report it (FDA 101: Dietary Supplements). Keep the bottle so the lot code is on hand.
- Sudden one-sided numbnessArm, leg or face, on one side of the body
- Face drooping, slurred speechOr trouble understanding speech
- Bladder or bowel changesLost control with back pain or numb inner thighs
- Weakness that spreadsGetting much worse over hours or days
- A foot sore that will not healOr a red, hot, swollen foot
SoonTingling, burning or numbness in the feet or hands that lasts more than a few weeks, keeps you up at night, or comes with diabetes, heavy drinking or chemotherapy: book a doctor visit and ask about B12 and blood sugar tests.
Call 911For sudden numbness or weakness on one side, a drooping face, trouble speaking, or sudden loss of bladder or bowel control.
Causes and warning signs from NINDS (NINDS, Peripheral Neuropathy) and MedlinePlus (MedlinePlus, Sciatica); foot sores from CDC (CDC, Your Feet and Diabetes).
Lower the risk08
How can you lower the risk of Nervecept side effects?
Lower the risk by checking the allergen line, clearing it with your pharmacist, and taking one capsule a day with water, never more.
Check
Shellfish or pineapple allergy: skip it.
Ask
Bring the bottle to your pharmacist.
Take one
One capsule, 8 oz of water, before a meal.
Watch
Note any change and stop if a problem starts.
FAQ09
Nervecept safety questions
Can Nervecept upset my stomach?
It can. Stomach upset and diarrhea are the most common reports for bromelain, and other ingredients cause mild gut effects in some people. Taking it with the full 8 oz of water may help; ask a pharmacist if it continues.
Does Nervecept cause drowsiness?
None of the eight ingredients is known for drowsiness in its safety sources. If you feel sleepy or dizzy after a capsule, stop it and tell your doctor, since another cause may be involved.
Can Nervecept raise my INR?
It may. Glucosamine with chondroitin can raise INR on warfarin, and a case report links quercetin to a rise too. If you are on warfarin, ask your doctor first and expect extra INR checks.
Should I stop Nervecept before surgery or dental work?
Tell your surgeon or dentist you take it. Several ingredients may affect bleeding, and NCCIH advises telling all providers about supplements before surgery. They will say when to stop.
Is Nervecept safe for my liver?
Probably at this dose, but not tested. Turmeric has rare liver injury reports, mostly with strong curcumin products. Stop and call a provider if you get dark urine, yellow skin or ongoing nausea.
How do I report a side effect from Nervecept?
Stop the capsule, get medical care if needed, and report it to FDA, as the agency asks. Keep the bottle and lot code, and tell the order desk at +1 (302) 200-3480 if you want a refund.
Who wrote this10
Written and reviewed by
Pages built from the label, the sales page and linked NIH, FDA, CDC, FTC and peer-reviewed sources.
Last updated . Read our editorial standards and how we check reviews. This website is run by a Nervecept licensed U.S. outlet, not by the manufacturer or the distributor. We earn money when you buy through our order links.
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